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(a) NG108 15 cells were transfected with plasmids encoding either GFP alone or wild type YFP tagged 5 HT6R nike free 7.0 australia or YFP tagged receptor mutant not able to activate Gs adenylyl cyclase (Gs dead) and treated with WAY181187 (WAY, 1 M), SB258585 (SB, 10 M) or rapamycin (Rapa, 100 nM). Cells were fixed, and neurite length was quantified (Supplementary Fig. 3a).

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